Virginiamycin (CAS: 11006-76-1; 270076-60-3)

Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin.

It is a combination of pristinamycin IIA(virginiamycin M1) and virginiamycin S1. Virginiamycin

is used in the fuel ethanol industry to prevent microbial contamination. It is also used in agriculture,

specifically in livestock, to accelerate the growth of the animals and to prevent and treat infections.

 Antibiotics also save as much as 30% in feed costs among young swine, although the savings fade

as pigs get older, according to a USDA study.

Applications

Virginiamycin (11006-76-1) can promote the livestock, poultry amino acid and phosphorus absorption

and utilization, improve feed conversion rate. Can be used for pig feed, the amount of 10 (10.2 million

units) to 20 (20.4 million units) g / t; also be used for 16 weeks or less of chicken feed, the amount of

2 ~ 5g / t, laying disabled. Its Gram-positive bacteria inhibition, can prevent bacterial diarrhea (such

as swine dysentery, chicken necrotizing enterocolitis, etc.), almost no resistance.

Production methods and other

Virginiamycin (11006-76-1) is prepared by: Virginia streptomycin (Streptomycesvirgint-ate) fermentation,

by extraction, precipitation derived. Virginiamycin (11006-76-1) quality indicators: [Department of Agriculture

standards (provisional)] raw materials: content (dry basis) ≥1020 titer / mg; pH value (1 + 1000 solution) 4.0 to

7.0; Loss on drying (60 ℃ decompression) ≤3.0%; heavy metal ≤0.002%; arsenic (As) ≤0.0005%; residue

on ignition ≤1.0%.

Chemical Properties

Beige powder. Good stability, stored at room temperature for three years, the same potency, can be stored for

more than six months in chicken feed. Rats orally LD507.5g / kg, mice oral doses of up to 1550mg / kg,

the no adverse reactions.

use 

Virginiamycin against Gram-positive bacteria inhibition can prevent bacterial diarrhea (such as swine dysentery

, chicken necrotizing enterocolitis, etc.), almost no resistance. In addition, to promote livestock, poultry amino

acid and phosphorus absorption and utilization, improve feed conversion rate. It can be used for pig feed in an

amount of 10 (1020 × 104U) -20 (2040 × 104U) g / t; also be used for chicken feed amount of 16 weeks or

less of 2-5g / t, laying disabled.