P-Toluenesulfonamide (CAS: 70-55-3)

Storage method 

1. With inner plastic bags, outer woven bag or inner, middle, with a brown paper bag, plastic bags
2. of outer woven bag packing. Stored in light with light, moisture, heat. According to provisions of
3. flammable toxic substances are stored.
4. This product should be kept sealed a cool and dry.

synthetic method

1. By p-toluene sulfonyl chloride and ammonia reaction. Process: first to amination pot add just the right amount
2. of ice water, then according to the ratio of quality (p-toluene sulfonyl chloride: pure ammonia = 1-0. 2)
3. measuring good p-toluene sulfonyl chloride and ammonia in turn into the pot, to start the mixer, using amination
4. pan pan jacketed cooling fluid control of temperature to 70 ℃ or so (the mass exothermic reaction, and then
5. cooled to discharge is about 30 ℃. Amine compound into the filter barrels, wash with warm water and blot is
6. solid powder products of toluene sulfonamide. Crude products of toluene sulfonamide contains a small amount
7. of by-product ortho body letter oily non-ferrous material. By using the properties of para amine soluble in sodium
8. hydroxide solution and using active carbon decoloring, can achieve purification refined. Ratio of material quality
9. for coarse registration amine: 30% sodium hydroxide liquid alkali: water = 100:00 aroused; Coarse registration
10. amine: activated carbon = 100: (2.5 3.5). According to the formula of the water and caustic soda in the purification
11. of the pot, open the jacket steam valve heated to 70 ℃, then add.
12. P-toluene sulfonyl chloride with pure ammonia, in turn, add to the ice water, control p-toluene sulfonyl chloride
13. and pure ammonia quality ratio is 1:0.2, under stirring reaction, cooling and control the temperature of 70 ℃.
14. After the reaction, cooling, filtering, washing products, products by caustic washing, bleaching, washing,
15. neutralization, filtration, washing, drying for a quick finished products.

Application

1. Used in organic synthesis. For toluene sulfonamide is mainly used for synthesis of chloramine -t and

tolbutamide chloramphenicol (Tevenel).

2. Used in the synthesis of fluorescent dye, plasticizer, synthetic resin, paint, disinfectants

and wood processing brightener, etc. 

3. Mainly used for synthesis of water-soluble melamine formaldehyde resin toughening agent.

4. As a primary brightener in the bright nickel plating. Used for light multilayer nickel plating,

uniform coating light. General dosage of 0.2 ~ 0.3 g/L.