Lestaurtinib CAS 111358-88-4

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Model: MOS 111358-88-4
Place of Origin: Shandong,China (Mainland)
Brand: MOSINTER
Melting Point: 215-220℃
Boiling point: 722.959°C at 760 mmHg
Density: 1.709g/cm3
Vapour pressure: 0mmHg at 25°C
Flashing point: 391.031°C

Lestaurtinib (CAS: 111358-88-4)

Item Index
Molecular Formula C26H21N3O4
Molecular Weight 439.469
Specification CP/USP/EP
Melting point 215-220°C

 Lestaurtinib (rINN, codenamed CEP-701) is a tyrosine kinase inhibitor structurally related to staurosporine, and is being developed by Cephalon.

It is an inhibitor of FLT3, JAK2,TrkA, TrkB and TrkC.

Uses

It is undergoing research for the treatment of acute myelogenous leukemia (AML) and myeloproliferative disorders.

As of 2009, it is in Phase II clinical trials for AML and Phase II clinical trials for myeloproliferative disorders.

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