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Guanidine hydrochloride CAS 50-01-1
DTT CAS 3483-12-3
05/06/2020
Guanidine thiocyanate CAS 593-84-0
05/06/2020
| Model: | MOS 50-01-1 |
| Brand Name: | MOSINTER |
| CAS No.: | 50-01-1 |
| Molecular weight: | 95.53 |
| Molecular formula: | CH6ClN3 |
Guanidine hydrochloride CAS 50-01-1
Description:
Guanidine hydrochloride is a white or yellowish lump. It is unstable. It can be hydrolyzed into
ammonia and urea in aqueous solution, so its toxicity is the same as that of urea. Guanidine and
its derivatives are generally more toxic than urea.
Specifications:
| Appearance | White crystal |
| Content | >99.50% |
| NH 4 CL | <0.30% |
| Ash | <0.05% |
| PH(4% In water) | 6.4±0.2 |
Application:
1. It can be used as medicine, pesticide, dye and other organic synthesis intermediates. It can be used
to synthesize 2-Aminopyrimidine, 2-amino-6-methylpyrimidine, 2-amino-4,6-dimethylpyrimidine.
It is the intermediate of manufacturing sulfadiazine, sulfamethylpyrimidine, sulfadimethylpyrimidine
and other sulfanilamide drugs.
2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate and cyclizes into
2,4-diamino-6-hydroxypyrimidine, which is used to synthesize folic acid, an anti anemia drug. It
can also be used as antistatic agent for synthetic fiber.
3. It can also be used as protein denaturant.
4. As a strong denaturant in the experiment of total RNA extraction. Guanidine hydrochloride solution can
dissolve protein, leading to cell structure destruction, nuclear protein secondary structure destruction, dissociation
from nucleic acid, in addition, RNA enzyme can be inactivated by guanidine hydrochloride and other reducing agents.
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