Fenbendazole CAS 43210-67-9

Apramycin CAS 37321-09-8
Tiamulin hydrogen famarate CAS 55297-96-6
Show all

Model: MOS 43210-67-9
CAS: 43210-67-9
Molecular formula: C15H13N3O2S
Melting point: 233℃
Refractive index: 1.709
Molecular weight: 299.3476
Density: 1.4g/cm3

Fenbendazole (CAS 43210-67-9)

Appearance White or almost white powder White powder
Identification Comp1ics with spcctrum of Fcnbcndazo1c CRS Complies
Total impurities ≤ 1.0% 0.3%
Impurity A ≤ 0.5% < 0.05%
Impurity B ≤ 0.5% < 0.05%
Any other impurity ≤ 0.5% 0.21%
Loss on drying ≤ 1.0% 0.1%
Heavy metals ≤ 20 ppm < 20 ppm
Sulphated ash ≤ 0.3% 0.1%
Assay (on dried basis) 98.0% ~ 101.0% 100.4%

Fenbendazole (Hoechst brand names Panacur and Safe-Guard, Intervet Panacur and Panacur Rabbit)

is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including:

giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms (but not effective against

Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles

and strongyloides and can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits and seals. Drug

interactions may occur if salicylanilides like dibromsalan and niclosamide are co-adminstered. Abortions

in cattle and death in sheep have been reported.


Despite being widely used as a dewormer in many species, toxicity has been reported. Birds (storks, pink

pelicans, vultures, pigeons and doves) and reptiles (vipers, turtles and tortoises) have shown toxicity

associated with bone marrow suppression, intestinal crypt cell necrosis and distal villi sloughing

.[citation needed] Abortions in domestic ruminants have been associated with concurrent use

of anti-trematode therapeutic agents.

Fenbendazole is poorly absorbed from the gastrointestinal tract in most species. The LD50 in

laboratory animals exceeds 10 g/kg when administered orally.


Fenbendazole synthesis


It gets metabolized in the liver to oxfendazole, which is anthelmintic too; oxfendazole partially

gets reduced back to fenbendazole in the liver and rumen. Also, fenbendazole itself is an

active metabolite of another anthelmintic drug, febantel.


There are no reviews yet.

Be the first to review “Fenbendazole CAS 43210-67-9”