Celecoxib (CAS: 169590-42-5)

Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID).

It is used to treat the signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain 

in adults, painful menstruation, and juvenile rheumatoid arthritis in patients two years or older.

Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction,

nonfatal stroke, or death from a blood vessel-related cause. Additionally, an 81% increase in incidence of upper gastrointestinal

complications occurs, which include perforations, obstructions, or gastrointestinal bleeding as in all NSAIDs.

It is marketed by Pfizer under the brand names Celebrex and Celebra for arthritis and Onsenal for polyps.

Celecoxib is available by prescription in capsule form.