Pharmacological action characteristics are similar to Enalapril, which has a strong inhibition effect of angiotensin converting enzyme. It takes effect quickly and for a long time, and can be taken once a day.The inhibition of ACE was 6 ~ 8 times that of captopril and 1 ~ 3 times that of benapril.Can make total peripheral resistance and blood pressure drop significantly, but do not have reflex tachycardia.Lisinopril can reduce pulmonary wedge pressure, increase cardiac output, increase left ventricular ejection fraction and improve cardiac function in patients with heart failure.It can increase renal blood flow, decrease renal vascular resistance and increase glomerular filtration rate.Use alone or use with other medicaments to treat the hypertensive disease of all sorts of degrees and kidney sex hypertensive that other antihypertensive medicaments treats inefficacy, also can use alone or use with digitalis, diuretics to treat congestive heart failure.It can also be used as adjuvant therapy for patients with stable hemodynamics after acute myocardial infarction.