Gentamycin Solution(CAS: 1405-41-0)

Applications

Gentamicin Sulfate Reagent Solution is recommended for use in cell culture applications at 5

ml/L and used as a selection agent (gentamicin-resistance gene) in molecular biology applications.

Product Description

Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora

purpurea or M. echinospora. It is a mixture of 3 major components designated as C1 (C21H43N5O7),

C1a (C19H39N5O), and C2 (C20H41N5O7). Gentamicin is used as the sulfate salt. Each component

consists of five basic nitrogens and requires five equivalents of sulfuric acid per mole of gentamicin

base. Gentamicin sulfate is a broad spectrum antibiotic. It inhibits the growth of a wide variety of

Gram-positive and Gram-negative microorganisms, including strains resistant to tetracycline,

chloramphenicol, kanamycin, and colistin, particularly strains of Pseudomonas, Proteus,

Staphylococcus, and Streptococcus. It is effective against mycoplasma as well.

Biochem/physiol Actions

Gentamicin Sulfate inhibits protein synthesis by binding to L6 protein of 50S ribosomal

subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.